SudaMediCa, The Sudanese Medical Community

Concise Magnesium Sulphate Protocol

Indications:

 Eclampsia.
 Severe pre eclampsia.
Contraindications:
• Neuromuscular disease.
• Myasthenia Gravis.
• Renal failure/ impairment
• Cardiac disease.
Management:
 Insert an airway and commence O2 by mask.
 Institute an IV line and take blood for investigations.
 Abort the fit by IV 10-20 mg Diazepam.
 Insert Foley’s catheter
 Start an ECG monitoring.

Mg.Sulphate Administration:
 Loading dose:
Inject 10% Mg.Sulphate (2X20ml), which is equivalent to 4 Gms,
Intravenously over 3-5 minutes.
The loading dose always causes nausea, vomiting and flushing. This is
Why Maxolon10mg or phenergan 25mg is given i.v. The mother should
Be warned that these symptoms may occur. They are nor signs of
anaphylaxis


 Maintenance Dose:
Infuse Mg.Sulphate continuously at a rate of 1-2 Gms per hour for 24 hours.
Option 1: 1 Gm per hour:
Incorporate (5X20ml) 10% Mg Sulphate (=10Gms) in 400 ml Dextrose
5% in water. Infuse at a rate of 50 ml per hour.